Synthesis of (1-substituted 1,2,3-triazol-4-yl)-7-deazapurines

Karolis Karpavičius; Kasparas Kižys; Sebastien  Leroy; Jolanta Rousseau; Jonas Bucevičius; Sigitas Tumkevičius

doi:10.6001/chemija.2016.27.4.5

Karolis Karpavičius
Kasparas Kižys
Sebastien Leroy
Jolanta Rousseau
Jonas Bucevičius
Sigitas Tumkevičius

DOI: https://doi.org/10.6001/chemija.2016.27.4.5

Keywords: 7-deazapurine, pyrrolo[2,3-d]pyrimidine, Sonogashira reaction, Stille reaction, 1,2,3-triazole

Abstract

A simple synthesis of 2-phenyl-6-(1-substituted 1,2,3-triazol-4-yl)- and 2,6-bis(1-phenyl 1,2,3-triazol-4-yl)-9-methyl-7-deazapurines from 2,6-dichloro-9-methyl-7-deazapurine has been developed.