Influence of the Chernobyl accident on the frequency of chromosomal damage and health status of Lithuanian clean-up workers

  • J. R. Lazutka
  • G. J. Rimdeika

Anotacija

Chromosomal damage and health status were analyzed in Chernobyl clean-up workers currently residing in Lithuania. Statistically significantly (P < 0.05) increased frequencies of chromosome-type aberrations (chromosome breaks, dicentric and ring chromosomes) as well as aberrant cells were found in the peripheral blood lymphocytes of clean-up workers when measured 6–8 years after the exposure. Significant health impairment was characteristic of tiese persons as well. On average, 5.6 diseases per patient were diagnosed in clean-up workers suffering from cardiovascular diseases. This high co-morbidity resulted in quite high rates of metabolic syndrome (16.7%). Among Chernobyl clean-up workers that had experienced post-traumatic stress disorder, 76% suffered from highly expressed sleep disturbances. Analysis of thyroid diseases among 500 clean-up workers has revealed that 27.6% individuals have different pathology of thyroid gland. Thus, even 20 years after the Chernobyl disaster, clean-up workers must be considered as a group of primary interest both for researchers and physicians. Keywords: Chernobyl clean-up workers, ionizing radiation, chromosomas damage, health status, metabolic syndrome, sleep disturbances
Publikuotas
2006-01-01
Skyrius
Genetics