Relaxation dynamics of guanosine 5’-monophosphate with Na+ and K+ in aqueous solutions investigated by broadband dielectric spectroscopy
Keywords:
dielectric spectroscopy, Na⁺ and K⁺ counterions, relaxation dynamics, biological matter, polyelectrolytes
Abstract
To gain insights into nucleotide–monovalent ions interaction, the dynamics of counterions (sodium and potassium) with guanosine 5'-monophosphate (5'-GMP) were studied in an aqueous solution via broadband dielectric spectroscopy measurements. Complex reflection coefficients of aqueous Na-GMP and K-GMP solutions are measured in the frequency domain at room temperature. Complex specific resistance spectra are analyzed at various mononucleotide concentrations. One dispersion region located at 100 MHz was observed. It is interpreted as being caused by DNA counterion fluctuations. It largely depends on the GMP concentration in the solution.
