The closed-loop coding-decoding concept as the general principle of functional organization in living systems

Abstract

The principal paradigmatic and structural schemes of the functional organization of life (organisms and their systems) are constructed on the basis of systemic analysis and synthesis of the main phenomenological features of the living world. Life is based on functional elements that implement engineering procedures of closed-loop coding-decoding control (CL-CDC). In this approach, living systems are technological systems that naturally emerged on the Earth 3–4 bln years ago as a result of chemical and, later on, biological evolution. Generalized schemes of functional organization on the levels of cell, organism and brain neocortex (as the highest one with CL-CDC) are presented. The CL-CDC concept expands the understanding of bioinformatics as informatic technologies in life sciences by showing information as the key player in natural processes. Keywords: coding-decoding, informational control, constructive biology, synthetic system biology, living systems